Vasodialation, chemical mediators increase permeability.
Edema and pain
–Clinical findings with acute inflammation determined by severity of reaction, cause, and size. –ranges from mild swelling / redness to abscess or ulceration.
–Usually self–limiting, short duration –Healing occurs in 2–3 wks usually with no residual damage. –Vascular changes, edema, neutrophils infiltration. –Sub–acute inflammation has features of acute process but last longer.
tonsillitis , cellulitis , PUD
–self–perpetuating, lasting weeks or more –injurious agent persists or repeatedly injures tissue. Infiltrate with macrophages , lymphocytes and attempted connective tissue repair with new vessel formation. –may be result of alteration in imm response.
IBD, hepatitis induced cirrhosis
Time of injury
Bad, bc of increase heat production
–Encouraging healthy cells to divide –Triggering new vessel growth and scar formation
EVERYBODY , but age can determine the degree of response.
Cannot manage the infx so a minor infx can go full blow quickly.