Produced from precursor factor kininogen as a result of activation of Hageman factor (XII) of clotting system.
Cause contractions of smooth muscle and vasodilation. Result in stimulation of pain.
Anaphylatoxic agents generated from complement pathway activation.
Stimulate histamine release and chemotaxis.
Produced from arachidonic acid
PGs cause vasodilation LTs stimulate chemotaxis.
Results from outpouring of fluid. Seen in early stages of inflammation or when injury is mild.
Skin blisters , pleural effusion
Found during the midpoint in healing after sx or tissue injury. Composed of RBCs and serous fluid, which is semiclear pink and may have red streaks.
Surgical drain fluid
Occurs with increasing vascular permeability and fibrinogen leakage into interstitial spaces. Excessive amounts of fibrin that coats tissue surfaces may cause them to adhere.
Adhesions, gelatinous ribbons seen in surgical drain tubing. Frequently covers fluid–exuding wounds such as venous ulcers.