Histamine (mast and basophils); Serotonin. they cause vasodilation and make vessels leaky
by activation of factor XII
Combination of complement proteins that punch holes in microbe membranes
A family of polypeptides that act locally to induce vasodilation, increased vascular permeability, and contraction of smooth muscle. They're rapidly inactivated by kininases.
peptide that causes blood vessels to dilate (enlarge), and therefore causes blood pressure to lower.
Cascade of plasma proteases ultimately converting soluble fibrinogen to insoluble fibrin clot (the physiological band–aid'
fragments of protein released from a dissolving clot. They increase vascular permeability. The fibrin split products test is one of several tests done to evaluate a person with blood clotting problems (coagulation), particularly disseminated intravascular coagulation (DIC).
break down fibrin clots
Fibrinogen: soluble. Fibrin: insoluble. forms clot.
1) Cyclo–oxygenase (prostaglandins) 2) Lipoxygenase (cause increased vascular permeability, vasoconstriction, bronchospasm)
Cyclo–oxygenase; cause vasodilation and prolong edema
Lipoxygenase; cause increased vascular permeability, vasoconstriction, and bronchospasm