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2 types of colony stimulating factors?
GCSF (granuloctye) and GMCSF (granulocyte macrophage)
TNF envolved in angiogenesis?
enhances it
TNF important in?
endotoxic shock
TNF increase?
cytokine (IL) production, phagocyte activity, PGI2 synthesis in endothelial cells
TGF stimulate for wound healing and collagen production?
fibroblasts
TGF mediate?
proliferation, differentiation, angiogenesis, cell migration and adherence
TGF increase?
interleukin production
widest acting cytokine?
TGF
Interferons are inducible and are synesized in response to what stimuli?
viral
types of interferons are there?
IFN alpha– cathectin, and interferon gamma and beta
What inhibits IL production and activity?
glucocorticoids and gold compounds
What vascular endothelial cells do interleukins act on?
NO, vasodilator